Jane is Professor of Paediatric Respirology & Experimental Medicine at Imperial College, London and Honorary Consultant at the Royal Brompton Hospital. She co-leads the site at the ECFS Clinical Trial Network through which they are engaged in many trials in the current pipeline. She has been global lead investigator for the first trials of CFTR modulators in young children and babies and is working on the standardisation of lung clearance index, a sensitive measure of pulmonary health in early disease.